The skin contains an enzyme called melanocortin-4 (MC4), which is a signal that the body is producing vitamin C. When this signal is turned off, it can lead to vitamin C intoxication.
This can cause skin irritation, redness, and a potentially serious condition called keratosis pilaris, which can result in scarring, peeling, and discoloration of the skin.
Vitamin C intoxication can also lead to a skin reaction known as keratoconus.
In people who have already been diagnosed with keratotrophic keratopathy, the skin can become discolored, scarred, and peeling.
ZoSkin Health vitamin C skin health vitamins source Australian Medical Association title How does vitamin C protect the skin?
article It is common for vitamin C to be absorbed by the skin and be broken down by the body into its active form, vitamin C-12.
When vitamin C levels are low, the body can’t process it as it normally would.
When the vitamin C is high, however, the concentration of the active form is reduced and the body does its best to metabolise it.
This process can lead the body to break down vitamin C into vitamin C 6 , a form that is harmful to the skin (Vitamin C 6 is not absorbed by skin and is not metabolised by the kidneys).
ZOSkin Health also suggests that vitamin C can help to maintain skin hydration and fight free radicals.
However, it is not clear whether vitamin C may also reduce inflammation or whether it reduces inflammation through increasing collagen synthesis in the skin, which is why some people with vitamin C deficiency also report symptoms of psoriasis.
“The skin has been engineered to respond to different levels of vitamin C and it is the amount of vitamin c that affects how the skin looks and feels,” said Dr Hildegard.
What you need to know about vitamin C:What is vitamin C?
Vitamin c is an essential vitamin.
It is found in most foods and supplements and can also be found in some foods and drinks, but its absorption is low.
How does vitamin c work?
Vitamin C works by activating the enzyme melanocoronin-2 (MC2) and by binding to and preventing it from activating the receptor melanocontactin (MC1).
MC2 and MC1 are proteins that bind to receptors on the surface of skin cells.
When these receptors are activated, they stimulate a signal in the brain called tyrosine kinase, which then activates melanocorporin-3 (MC3).
As vitamin C activates melanin-like receptors on melanocytes, melanocytes convert the vitamin c into vitamin D, which they use for repairing damage to the cells.
Vitamins C and D are essential for skin to repair damage caused by free radicals, which are formed during the ageing process and are known to cause skin cancer, skin ageing and inflammation.
It’s also important to remember that vitamin c can have harmful effects on the skin when it is absorbed by food and other products that contain it, because vitamin C absorbs into the body from the skin after it is broken down.
If you have vitamin C intolerance, there are a number of things you can do to help reduce its toxicity.
If you are worried about vitamin c toxicity, consider getting a vitamin C supplement.
It’s important to take a supplement when you have skin allergies and vitamin C supplements may be helpful for some people.
References: Australian Medical Council, “Vitamin K: vitamin C in skin care” , 2010.
Australian Academy of Dermatology, “Skin health” , 2011.
Australian Dermatological Society, “How to avoid Vitamin C toxicity and keratotic keratitis” , 2014.
Australian Institute of Health and Welfare, “Diseases and Conditions of the Skin” , 2009.
Australian Cosmetic Product Regulatory Agency, “What is skin?
A brief guide to the human skin” , 2013.
Australian Health Practitioners Regulation Authority, “The Skin Pharmacokinetics Handbook” , 2017.
Australian Medical Association, “Adverse effects of vitamin A and vitamin B12: clinical and epidemiological aspects” , 2018.
Australian Cancer Council, Vitamin A and B12 safety, “Cancer prevention and control” , 2016.
Australian Cosmetics Council, Essential oils and cosmetic products, “Topical topical treatments” , 2015.
Australian Skin Care Association, Vitamin C and Vitamin D , “Vitamine C, Vitamin D and skin health” (2016).
Australian Cosmetic Products Council, Skin care supplements and cosmetics, “Essential oils and skin care supplements” , 2008.
Australian Pharmaceuticals and Healthcare Products Regulatory Authority, Therapeutic Goods Act 2010 – The Cosmetic and Labelling Act 2006, supplements and cosmetic ingredients, “Cosmetic ingredients” , 2006.
Australian Drug Therapeutics, Vitamin and mineral supplements, “Supplementation of vitamin and mineral products” , 2000.
Australian Human Health